منابع مشابه
Immunogenetics of trophoblastic tumours.
The fetus is an allograft foreign to the mother by the hemizygous set of paternal alleles. In a randomly mating population the mother may be incompatible with the fetus at any locus and the chance of incompatibility is increased according to the number of alleles at that locus. The persistence of the normal human fetal allograft is a puzzle that continues to intrigue biologists. The immunobiolo...
متن کاملThe histopathology of trophoblastic tumours.
Two important advances in the last 40 years have had a profound effect on the prognosis of patients with trophoblastic tumours. In the first place the application of gonadotrophin assay, initially by biological methods and then by the more accurate radioimmunological methods, to the diagnostic problems of patients with trophoblastic disease has made their management considerably easier. Secondl...
متن کاملGATA3 expression in gestational trophoblastic tissues and tumours.
AIMS GATA3 is a zinc-finger transcription factor that is important for trophoblast differentiation. GATA3 is sensitive for urothelial and breast carcinomas, but the specificity is low. The aim of this study was to investigate the expression of GATA3 in trophoblast-related tissues and neoplasia. METHODS AND RESULTS GATA3 immunohistochemistry was performed on 33 placentas, one atypical placenta...
متن کاملMolecular genotyping of placental site and epithelioid trophoblastic tumours; female predominance.
OBJECTIVE To investigate a large series of placental site trophoblastic tumours (PSTT) and epithelioid trophoblastic tumours (ETT) and determine the relationship between their development and the type and sex of both the immediately antecedent and causative pregnancies. METHODS The antecedent pregnancy was determined from patient records in 92 cases with a confirmed diagnosis of PSTT, ETT or ...
متن کاملTrophoblastic disease.
a Department of Obstetrics and Gynecology, University of Hong Kong, Queen Mary Hospital, Hong Kong, China b Department of Gynecology and Obstetrics, Yale University School of Medicine, New Haven, CT, USA c Department of Obstetrics and Gynecology, USA hCG Reference Service and Dagger Department of Biochemistry and Molecular Biology, University of New Mexico Health Science Center, Albuquerque, NM...
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ژورنال
عنوان ژورنال: BMJ
سال: 1963
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.5368.1303